From this article cometh these words of wisdom:
“Choose your small carry gun to be similar to the big gun you shoot best.”
…because in almost all cases, the “pocket” guns are more difficult to shoot than the regular “big” guns.
I can attest to that, because my “backup” S&W .38 Airweight is not just small, but teeny. That said, it is my backup and I almost never carry it as my primary piece — i.e. I carry it when I go to check the mailbox inside the apartment complex — because I know that in terms of results, my 1911 is an order of magnitude better in my hands.
However, the question then arises: why carry the Airweight at all?
Maybe I should dump the little revolver in favor of something like the “pocket” 1911:

And the budget option:

…although because it’s a carry gun, cost is not really an issue because my life may depend on it. That said, the Girsan has garnered plenty of good reviews from the people who use them.
I’ve carried a Colt Officer (and their Combat Commander) before too, so no issues there.
Of course, I’d stick with .45 ACP over any other cartridge (200 words of explanation plus innumerable past writings elided), and yes, I’d prefer a 1911 action because in my time I’ve shot more 1911 handguns than all the others combined, so why bother to learn a new action? [/OldFart]
It’s definitely something to chew over.